a term often used instead of and meaning "holy shit" either by a young person in front of there parents to avoid getting an ass whooping or by a young person in front of peers as a term of surprise, shock.
A variation on the Mexican "Mole" sauce. The phrase was coined to describe a Mole sauce which was so purely hot that it cleansed not only your bowels but your soul as well. However over time the meaning changed to mean simply a frightfully shocking occurrence.
"This salsa will burn it's way in and out!"