To go MIA, hibernate or go into hiding, sometimes with a loved one. The person often doesn't respond to texts or calls during this time. They might be depressed, need a break from the world, or are just busy having tons of sex with thier significant other.
Suz: What are you doing this weekend?
RC: My boyfriend and I are going to hole up and shut out the world until Monday.
Stop; See the word, Wayte. Adlib used by Rapper/Entertainer/Singer/Songwriter Bless Dogg (I AM Romeon).
Someones making to much noise, you tell them to "Hole up."