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1.
When you need to get laid and either have not, cannot, or refuse. Similar to a hotfix for software purposes, a hofix is a quick stop-gap measure to stop someone from being an insufferable asshole by getting them laid.
"Ann Coulter would be so much less of a bitch if they'd simply get her a hofix"

"I was in critical state until I deployed a hofix which will keep me running at capacity at least through the holidays"
by Marcellita November 22, 2011