Top Definition
A very fat and grossly overweight hoe, slut, bitch, whatever you'd want to call her.
One of the signs that indicate that the world's going to end soon, is waking up the next morning only to notice some ugly smothering hoepopotamus lying next to you like a beached whale and then being shocked to having realized that you've actually got her pregnant!
by Mark H September 01, 2004
1 Word related to hoepopotamus

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