Slang for prostitute aka whore aka hooker aka street walker aka call girl
According to the 7th Circuit Judges in the case of the United States vs. Murphy and Baker:

Footnote 1 The trial transcript quotes Ms. Hayden as saying Murphy called
her a snitch bitch “hoe.” A “hoe,” of course, is a tool used for
weeding and gardening. We think the court reporter, unfamiliar
with rap music (perhaps thankfully so), misunderstood Hayden’s
response. We have taken the liberty of changing “hoe” to “ho,” a
staple of rap music vernacular as, for example, when Ludacris
raps “You doin’ ho activities with ho tendencies.”
by JNJ May 06, 2005
hatems mum .
your mums a ho .
by your mums pimp March 01, 2005
Given no meanen to Ho Ho Ho
You a ho, Buh yo Mama smells like a toe.
by Anonymous March 15, 2003
means hello.....hi....hey.....etc
- ho man watup

-hohoho hows it goin?
by ppppppppppppppppppppppp August 28, 2005
A woman who cheats and runs around on her man.
Aries MH
by Lust Pollution September 16, 2003
an STD spreading ugly man looking individual, that thinks its cute ,and has sexual contact with anyone who will have it with her/him.
ho,A nasty girl that knowingly spreads STD's
by gangster grillz July 13, 2008
Acronym: Hand-jobs Optional
The Ho is here with me, for a price.
by Who I am October 07, 2007

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