When one is so desperate that they feel the need to resort to fucking a hippo.
Serj- "Daron! Groupies!"
Daron- "Are they hot?"
Serj- "...Dude, I'd fuck a hippo right now. I don't care!"
by Urine May 12, 2003
adverb, intensifier (usually negative); stronger than 'motherfucking'
My iPhone broke again! This thing is a hippofucking piece of shit!
by Aristoph November 14, 2008

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