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1.
1) A really screwed up disease that causes hallucinations and paranoia so intense you kill those around you and eventually yourself, usually by clawing out your throat.

2) What would happen if dementia and AIDS had a baby
*On the local news* "Sadly, another person suffering from the highly dangerous Hinamizawa Syndrome slaughtered their family, and then died moments later in the street after clawing out their own throat"
by Savior Ryuugu March 09, 2014