high: under the influence of a mood-affecting drug or (less common) alcohol.
breed: to arrange the mating of specific animals.
hybrid: offspring resulting from cross-breeding different entities, e.g. two different species or two purebred parent strains.
highbreed: to arrange the mating of different animals that are under the influences of a mood-affecting drug or alcohol.
"People wanted to 'highbreed' a drunk tiger to a high cat." - says a satirist