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1.
an alcoholic drink consisting of some form of liquor, esp. rum, whiskey, vodka, diluted with soda, water or ginger ale. served with lots of ice in a tall glass.
"all we've got is some popov and some sprite, guess we're drinking high balls tonight"
by King Chode November 26, 2004
 
2.
A short 1oz (mostly) drink. The hard is usually from the front bar (Rye, Vodka, White Rum, Tequila, etc) mixed with a soft drink or juice. Can be doubled or Tripled.
Cheap Highballs can include: Rye&Coke, Rum&Coke, Screwdriver, Vodke Slim, etc..
by Klautt July 18, 2005
 
3.
a drink: whiskey mixed with ginger ale
getting drunk off highballs is easy because it just tastes like ginger ale, so you're basically just drinking a lot of soda
by (high)ballin August 29, 2008
 
4.
An undescended testicle. Usually a birth defect, due to weak man-chemicals. But sometimes the result of a well-placed kick.
The bar slut asked me, "What's your favorite high ball?" And I replied, "I just have the one."

I was upset when my wife accused me of staying out all night sucking down high balls.
by Gandy Bird July 16, 2012
 
5.
A game originated in a neighborhood in the great northeast of philadelphia (Morrell Park). Created by a small group of morrell park hooligans. The small group of friends never let anyone know the exact rules of the game. All that is know is that a water bottle is thrown around after the kids smoke marijuana.
Your friendly neighborhood potheads. High ball
by Urban dictionary forum February 04, 2013
 
6.
To take the absolute greatest estimate of something
Boss: How long will it take you to do this
Guy: Well, to high ball it, I'd say about 2 hours
by Threads_Of_Fate August 13, 2012
 
7.
The physiological response of the human eye upon ingestion or inhalation of 'The Weeds'. The resulting response is characterized by a noticeable glossiness and/or a distinctive red discoloration of the whites of the eyes. A human showing signs of 'highballs' will often be hard to agitate, irritate, or otherwise provoke into any actions involving any materials other than Doritos or Shark Week.
"Dude, are my highballs showin? I don't want the cops knowin' I've been hitting The Weeds."

"Hey man, before you head to work take these eye drops for your wake and bake highballs."
by Jahngad August 17, 2014