Top Definition
A deadly trifecta of the most horrible and common STD’s. Notorious for causing discomfort while urinating, sores or lesions on the male or female genitals and inability to fight off infection.

pronounced - herpe-syphil-aids
Girl 1: Trent might be hot but he is a man whore, I hear he has herpesyphilaids.
Girl 2: Damn, nevermind.

I just got tested for the first time and came back clean; I can't believe don't have herpesyphilaids after college.
by lindy September 10, 2007

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