Top Definition
The worst Sexually Transmitted Disease (STD) a person could ever contract. It is comprised of the following: herpes, gonorrhea, syphilis and AIDS.
"I just got back from Vegas and something really itches and burns down below!"
"Oh, I think you've picked up herpegonosyphilaids...sounds like what happened in Vegas didn't stay in Vegas!"
by buffy3 June 02, 2009
3 more definitions
As the name implies, the worst STD you can get. Originated deep inside the jungle of your mom.
I got herpegonosyphilaids when I fucked your mom doggy-style.
by DrexlSpivey777 August 02, 2012
When you're not sure what the skank in the corner has. You have to assume she has ....herpegonosyphilaids
Yo man! you better stay away from that ho.... That bitch got herpegonosyphilaids..
by QDAWG1 November 01, 2007
The most deadliest of all S.T.D.'s. It is the combination of Herpes, Gonorrhea, Syphilis, and AIDS.
Thanks to herpegonosyphilaids, I can't even breathe around others without getting them infected!
by James Jarvis January 25, 2005

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