Top Definition
Any orifice of the body that is infected with herpes, although usually refers to the genitalia.
Person A: "Um, so can I crash at your place tonight?"
Person B: "What's wrong with yours?"
Person A: "My skank-ass roommate is going to be getting a dick rammed into her herpe hole"
by duchess of bong hits April 05, 2011

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from We'll never spam you.