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1.
noun - A person with XY chromosomes that acts overtly machismo and flirtacious to anything with a vagina in a manipulative attempt to receive some kind of sexual stimulation by night's end. They are often applauded by their fellow he sluts and suffer from a sense of grandeur following each successful attempt. However, he sluts are bullshit artists that carry and transmit a host of venerial diseases and thus can be considered a public health issue.
"Can you believe that he slut tried to hit up Tara, Kelly, and I all on the same night?!"
by HeSlutz.com December 06, 2009
 
2.
A man or boy who intentionally gets drunk or high at a party so he is able to cheat on his girlfriend without feeling guilty.
1) You're such a he slut.

2) I am not a he slut. I was drunk, it didn't count.
by wilded August 31, 2009