To make a large amount of money from some activity
"If you opened a new bar in the swanky part of town, you would have it off"
by Glen Scott August 04, 2006
2 more definitions
1. Verb, to have sex (in any form). Usually quick or very intense sexual encounters due to secrecy, emotional baggage, timing, or relationship unavailability of you or the other person involved. See also nooner.
1. I wonder how many Real World contestants had it off when the cameras weren't rolling? I'd definitely have it off with Dan Renzi.
by dancingqueen March 07, 2005