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1.
1 - when you have a lil feeling nagging in your head telling you to do or not to do something
2 - an awesome song my eMINEm as SarahMarie would say
1 - Ah my conscience is acting like my damn Mom
2 - Meet Grady, a 29 year old construction worker. After coming home from a hard day's work, he walks in the door of his trailer park home to find his wife in bed with another man.
"WHAT THE FUCK?!?!"
2 - "Wait! What if there's an explanation for this shit?"
"What? She tripped? Fell? Landed on his dick?!?"
by *MICHI* August 13, 2003
 
2.
When someone is so defensive about something being true/false, that it is obvious that they want the opposite.
Dan: LOL you have a crush on Kyle, don't you Erica?

Erica: NO! What are you talking about! That's the stupidest thing I have ever heard! Kyle is the last person i would ever like, EVER! He is definitely NOT the cutest boy I have seen in my life, and I definitely do NOT want him in my pants!

Dan: Tsk Tsk *waves finger*. does someone have a guilty conscience?
by Lateonalto February 17, 2009
 
3.
A feeling you get when someone has called your bluff.

When you feel ill and sick to your stomach because you are the cause of a hurtful situation. You try to deny it to yourself but that feeling won't let you.
So, you go shopping with your friend, then go home and talk shit about them to your mate. Then your mate repeats what happened shopping, word for word to another friend and that friend then goes back and tells. BUSTED!! You should have a guilty conscience!
by Heatherdog December 22, 2009