Extremely intoxicated to the point of no return.
Your
gullet is a funny word to describe your
mouth, throat, and stomach region, hence an individual who is off their gullet
may be projectile vomiting as a result of being so intoxicated
Frat
guy: “Dude you gotta get up, your ride is here!”
Dude who is fighting for his life on the toilet: “I
literally can’t
guy, I’m off my gullet.”
His ride: “How much have you drank dude? You are off your gullet!”