look up any word, like ratchet:
 
1.
breaking wind, letting rip, farting
phewwww can you smell that i've just guffed!!!!!!
by marie August 05, 2003
 
2.
To COMPLETELY dominate somthing or someone
I totally guffed you up
by DFG January 14, 2003
 
3.
to be completly off your face on weed

comes from south affrica
u look competly guffed
by wierd is a good thing February 10, 2005