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2.
When a man has taco shits, or some form of the shits combined with any spicy food, or any other substance which causes a burning sensation comming out of the asshole, and said man wipes back to front.
Goodness gracious man, I have great balls of fire!
by Poisonhole October 17, 2008
 
1.
An extreme case of JockItch.
... goodness, gracious, great balls of fire!
by Jerry Lee Lewis November 28, 2006
 
3.
when a girl lights her man's pubic hair of his balls on fire then proceeds to put it out by having her best friend pee on them.
goodness gratious, that dude has great balls of fire.
by Taylor Holley November 16, 2004