Top Definition
It's like an 'olly olly oxenfree' for your bowels, stomach and bladder. An involuntary reaction that causes one to vomit, shit and piss himself. This most often occurs during level 5 drunkenness or sometimes while sneezing violently.

It's rumored that grafundalo is an onomatopoeia of the sound one makes during the ordeal, or that it is a bastardization of an Italian word.
"If you slam that bottle of rot-gut tequila after Taco Tuesday, you're heading for a grafundalo."
by Barry Regal January 26, 2013

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