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1.
an excellent and rare opportunity
This is my golden opportunity to redeem myself.
by Light Joker June 09, 2005
 
2.
Drunkenly peeing the bed when company is over and blaming it on them in the morning
"Dude, did you bang that chick last night?"
"Yeah bro, but I was so wasted I pissed the bed"
"Did you blame it on her in the morning?"
"No, why?"
"Then you, my friend, missed a GOLDEN OPPORTUNITY"
by Hellatightshit January 06, 2010
 
3.
A great, often unexpected chance to achieve a desired goal.
I blew a golden opportunity when I left my homework pass at home after deciding not to do my homework.
by Diggity Monkeez January 04, 2005