Ted: I think he got too drunk last night and ended up going rogue.
Chris: oh no, not with that tranny!!!
Levi: Yeah Bristol, I'm sure glad your Mom was "Going Rogue" and the bear got one whiff of that and ran like hell.
has nothing to do with anal sex thats a joke from somebody as you noticed its several different vulgar definitions earlier so none of them matter because going rogue means dissapearing. can also mean getting drunk and blacking out