Origins: TRyP from irc created the greg when he explained how he had slept with multiple women at once, then came onto irc and confessed he had advanced HIV and AIDS.
2. Person on IRC who has recieved advanced HIV and AIDS from coming in contact with someone who has the greg. "Hey did you he that <PoorlyToldJoke > got the greg?"
3. When you get fired from a low paying job after working only a week. "Hey dude, i heard that your boss gave you the greg."
4. Being addicted to cocaine. "Hey i had to go to rehab for getting the greg."