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1.
Used to describe something so horrible that it can spontaneously infect victims with the HIV virus and instantly advance to full blown AIDS.
The YouTube movie you and your friends made was so lame that watching it gave me aids.

by dawg2 October 19, 2006
 
2.
A term used in the mmorpg World of Warcraft to describe the act of passing the PvP (player versus player) status to other members of your party on PvE servers.
Raid leader: Before the raid begins please buff everyone.
Raider1: Aww man, who the hell gave me aids?
Raider2: It was Nubsauce. He was flagged when we invited him!
Raid leader: Nubsauce please turn off your pvp status so everyone in the raid doesn't get aids!
Raider1: Dammit I was at the stone and just got ganked.
Entire raid: (In unison) wtg Nubsauce!
by Awkwardadam June 09, 2009