Top Definition
1) the muscles that flex in the back of your head when you laugh.
2) uncontrollable laughter caused by a nice fatty boombatty blunt.
(guy 1): yo man i'm feelin it.
(guy 2): yo man... me too.
(guy 2): yo this nigga guy 1 got the ganoobies.
by waudi c. wilkins August 05, 2003
1 more definition
8 Words related to ganoobies
also, gannobied or ganoobified.
the state of being high and laughing uncontrolably.
"I smoked so much weed last nite that i had the ganoobies!
" You are hella ganoobied, man!"
"Let's go get ganoobified!"
by jizosh420 March 30, 2004

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