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1.
The compulsive need to over accessorize, or cover up, to hide flaws.
"Damn that bitch is got some serious gaga syndrome."
"Don't complain dude, I don't want to see that shit without hair in its face."
by Kurt 8 Keiner December 01, 2009
 
2.
When a certain person becomes completely obsessed with Lady Gaga and tries to mimic her hair, makeup, clothing, and singing style he or she has Gaga Syndrome. But if you try to copy Lady Gaga's awesomeness only one thing can happen--you fail miserably. Side-effects might include making music videos where you say that you "Can't be Tamed", having wings in the video, or a huge amount of makeup on (*cough cough MILEY CYRUS cough cough*).
Did you see Miley Cyrus' "Can't Be Tamed" video?
Yeah! She has a serious case of Gaga Syndrome!
by THISISMYPSEUDONYM! June 18, 2010