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42.
To have sex with the girl on top.
I would love to fuckup Lucy Liu .
by JoeMartines October 04, 2006
7 24
 
1.
Pretty much an accurate description of the Presidency of George W. Bush.
The economy, No Child Left Behind, the Iraq war, the budget, and the tax cuts are all example of Bush's numerous fuck ups.
by Jesse January 24, 2005
1651 688
 
2.
A failure, someone who really messes up.
Omg you're such a fuck up.
by FreD July 23, 2004
930 238
 
3.
1. To make a mistake; bungle something.
2. To act carelessly, foolishly, or incorrectly.
3. To cause to be intoxicated.
Fucked up fucker.
by Sam429 March 12, 2004
611 232
 
4.
An extreme disappointment, someone who continually makes foolish mistakes and doesn't learn.
"Dave was a fuckup. He was constantly ruining good situations for selfish reasons."

by LKR December 29, 2005
253 76
 
5.
A failure at everything, total loser, unable to do anything right
Barry you fuck up!
by Barry... how ironic? March 28, 2003
350 181
 
6.
A complete elmore or screw up.
You, sir, are a complete and utter fuck up. Good day!
by James Bullwinkle September 26, 2007
213 118
 
7.
1) Mess up, screw up, failure, mistake
2) Also can be used to say shut up in a more excessive way
1) You're a total fuck up
2) Shut the fuck up!
by Whale watcher April 22, 2003
214 123