look up any word, like dirty sanchez:
 
1.
To defeat, obliterate, destroy, harm, or damage.

Derived from the euphemism "to fuck up," and "shit,"defined as objects or belongings.
Synonyms: own, pwn

Not to be confused with fuck shit up
That chem exam fucked my shit. I failed for sure.
by thehurricane7 October 04, 2010