Top Definition
A phrase used to express utter frustration in a variety of applications, usually caused by the force of a barbara. Fuck barbara, fuck! Including but not limited to frustration due to intoxication to the point of becoming best friends with a toilet and laying on the floor in pain, unable to get up...possibly insinuated by excessive playing of the song "Roxanne", at a party, with drinking cues provided by a barbara. This frustration is not necessarily towards a barbara, but is more applicable in situations where a barbara fucks with someone's life.
Barbara - "Roxanne!" (points to one group)
- "Red Light!" (points to other)

..continued cycle through song completion

10 minutes later...

Barbara, "Oh shit, Megan are you sick?"
Megan, "...fuck barbara!!".
by barbv12 January 31, 2009
5 Words related to fuck barbara!

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