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dont know your ass from the ass end of a bowling ball 

dont know your ass from the ass end of a bowling ball similar to dont know your ass from a hole in the ground a little more funny
you mister president dont know your ass from the ass end of a bowling ball

Piss come from my ass!!! 

Expletive spoken as a tic from a citizen of South Park with tourette's syndrome. While other residents had boring tics like snapping their fingers and grimacing, this particular man shouts various combinations of "piss come from my ass" in succession.
"Whats up, South Park guy!"

"Hi how are... p-p-PISS come from my ASSSS!!! Piss... Ass. Piss COME from my ASS!!!!!!!!!! ahem. excuse me, I meant how are you doing? ASS PISS ASSSSSS!!!!"

don't know your ass from a hole in the ground

It means you don't know any better or not up for the job.
Son you don't know your ass from a hole in the ground What makes you think you can do this?

you don't know your ass from a hole in the ground 

Figure of meaning that someone doesn't know what they're doing.
You don't know your ass from a hole in the ground.

ass from a hole in the ground

He doesn't know his ass from a hole in the ground.

blast from the ass 

Jimmie let a blast from the ass.