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1.
Use of American Sign Language (ASL) in a bar or club to pick up a man or women for the purpose of sexual relations. Because of the use of ASL non participants in the conversation "get" the basics of the conversation.
"I can see from here that Bill is asking Tony to spend the night. He's showing frisky hands."

"Look, at those frisky hands! Tom just asked Mary to go play at his apartment.
by Lyoninthesun July 03, 2010
 
2.
A compulsive need to touch your female friend, even when she tells you not to. Ultimately leads to you sleeping on the floor.
'Did you just touch my bum?'
'No!'
'I know it's peachy but you and your frisky hands need to learn some self control!'
by lbradders January 26, 2010