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1.
An affliction where one has the tendency to slip up in a conversation and eat their own words.

see: open mouth, insert foot
I accidentally insulted Joe's mom right in front of her. I think I have foot-in-mouth disease.

Most politicians suffer from foot-in-mouth disease; they make promises that they never keep which eventually bites them in the ass.
by Baz S. October 04, 2007
 
2.
A description about one who has a habit of putting their foot in their mouth. From Foot and Mouth Disease.
"Oh, Geez, I'm sorry!" Bob said.
"You've got foot in mouth disease today, don't you?"
by armina August 10, 2005