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62.
it is a word ghetto fabolous word crated by Snoop dogg for the sayin
Fo real my nigga
My mom died
Fo shizzle my nizzle
by anonamis my nizzle March 29, 2005
 
1.
"fo shizzle ma nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother"
by Anonymous November 10, 2002
 
2.
1.) A shortened form of the phrase "Indeed, that is a prodigious idea, my African-American brother!"
Would you desire some more orange flavoured soda?

fo' shizzle my nizzle!
by Manawski March 30, 2003
 
3.
"I concur whole-heartedly, my African-American brother"
Hello, wouldn't it be great to go for a drive in my 1964 Impala, while drinking a 24 oz alcoholic beverage, to attempt to copulate with members of the opposite sex?

"I concur whole-heartedly, my African-American brother"
by Jimmy J April 07, 2003
 
4.
David Letterman said it best: I don't know what the fizzuck I'm talking about.
by David October 12, 2003
 
5.
for sure my nigga - derived from our friend william shakespeare
"fo shizzle or no fo shizzle that is the quizzle my african american bizzle"
by Dudette9 May 22, 2005
 
6.
Meaning:
1. affirmative; For sure, ma nigga

not necessarily in any racial context.
From a branch of urban (American) slang which adds 'izz' or varients of (ie izzle/izzo) to words to create a more rhyme like 'melody' to sentences.
kid 1: "It's late, I'm heading back to the hizzous... you stayin?"

kid 2: "fo' shizzle my nizzle"
by theJudge August 09, 2003
 
7.
1. A polite and well meaning colloquialism used to express agreement with a cohort. (This phrase entered american vernacular when famed celebrity/artist/rapper/pornographer/movie star Snoop Dogg started using it and other words containing the suffix "izzle" or "izzy.")

2. To aquiesce to or agree with a proposition or idea offered by an affable peer.
My Boy D-Bo axed me if I was going to the game tonight... I said "Fo' Shizzle my nizzle" in the pitch of a tenor.
by Barry February 12, 2004