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64.
For sure my nigger.
Dr. O: 'Hey Millsy, you goin' to the show?'

Millsy: 'Fo shizzle my nizzo!'
by Millsy September 14, 2003
 
1.
Literally meaning yes. A ghetto slang term derived from 'for sure, my nigger'.

Also. Fo' shizzle my nizzle.
Also. Fo' shizzle mah nizzle.
You got AIDS?
Fo' shizzle my nizzo!
by Lexicon Master September 15, 2003
 
2.
Idiomatically translated: This is for sure-as in one would know this fact to be true.

Literally translated: FOR SURE MY NIG*A
TYRONE: Did you pass that difficult biology class at Harvard last semester?
KEYSHAWN: "fo shizzle my nizzo"--- Of course I passed the class with flying colors only to affirm my position on the Dean's List. How could you make such a ridiculous inquiry as to question my unlimited abilities?
by \'YO MAMA\' September 04, 2003
 
3.
A dazzled up way of saying "for sure my nigger" Originally used by african americans such as: Snoop Dogg and Jay-Z but over-taken by wiggers such as Justin Timberlake because of it's easy-speaking nature.
"Fo shizzle my nizzo! Dirty Pop sure was a great N*Sync hit!"
by Kristen December 01, 2003
 
4.
Explicit. An ebonic version of the phrase: For sure, my nigger. Used as a means of assent or agreement with a trusted companion.
Negro 1: Yo' wanna party wit' me?
Negro 2: Fo shizzle my nizzo
by Azmodeus September 17, 2003
 
5.
For sure my man
Are you going? Fo shizzle my nizzo
by Will D. Chill September 16, 2003
 
6.
Meaning fo-sho My Nigga ..
Aye Mike You going to the party tonight?
*fO Shizzle my Nizzo*
by Stl_Cutie September 16, 2003
 
7.
for sure my nigro (snoop dogg)
are we going to the park? Fo Shizzle My Nizzo
by Chris Toal September 16, 2003