Top Definition
the feeling of boredom one experiences after eating some percentage of a (usually) large portion of food that has pushed their taste buds to the limits of tolerance for the same food. flavor fatigue can be embarrassing because one may have been excited to eat their favorite pasta, but halfway through their meal has become bored with the flavor and wishes he or she did not have such a large amount of leftover food.
After eating through half of his massive cheeseburger, the boy became afflicted with flavor fatigue and wished he had simply ordered some chicken fingers instead.
by DJDonkaJunce July 08, 2010

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