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n. Short for police officers. Originated from the TV show Hawaii 5-0 which was a copp show in the 1970's. Hawaii is the 50th state, hence the nickname "5-0".
Put that blunt out, five-o, five-o!
five-o by thug4life September 29, 2002
refers to police / law enforcement. From the TV show "Hawaii 5-0" about the 50th State's Police Department.
"Are you mofo's 5-0 ?? "
five o by CCC_Trinity June 9, 2005
Urban slang for police officers. Derived from the police drama "Hawaii 5-0."
Five-O is following us, and we've got six bags of crack in the trunk. Damn, we're doomed.
five-o by GuidoPosse69 February 8, 2005

five - o 

A generalization of the name of the Honolulu Police (as in the old TV program "Hawaii 5-0") to refer to any police agency or generic cop(s).
Douse that doob, man, the five - o is on our ass!
five - o by LYQUOR July 19, 2007
Five O - n. its very simple this word = THE POLICE!
The Five O likes to beat on minorities.
Five O by Kale April 20, 2006
A term used for police. Usually when the person is doing something wrong or illegal.

police pigs
Shit! Run! The Five-O are coming! Hide the drugs!
Five-O by Ziggy Bop March 7, 2008