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1.
1. When you're giving some dude a hard-ass fisting and your fist tears through his colon and ends up inside of his sac.
2. A fist that has replaced one or both of the testes as a result of deep violent fisting.
The mayor puked up his salmon dinner when I gave him a fisticle.
by Selur Natas September 09, 2004
 
2.
Using your fists as spectacles to see far away objects seem a little bit more focused.
"I don't have my glasses, I can't read this book"
"Well why don't you use your pair of my patented fisticles"

-From the fisticles infomercial.
by Frankletini November 07, 2010