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2.
A cut inside your anus. A.K.A. "Butt hole cut"

"My anus is bleeding!!! Damn fissure!"
by clarkfisherismygslice November 06, 2007
 
1.
Open wounds in the skin. Usually gaping and the source of a nasty odor, they usually occur on or around the anus and buttox areas. See George W Olson for an example.
The rot that lives in George's gaping fissures forced me to sleep on the couch.
by Rob Kudla February 22, 2004
 
3.
Caused by the stuffing of bananas up the anus.

Often experienced by veteran porn actors. e.g. Bree Olsen, Carmella Bing, Gianna Michaels, Flower Tucci.
Bill: 'Arghhh, too many bananas'. FISSURE!

Alana: 'hehehehhe'
by yokel of Melbourne August 30, 2008