Top Definition
n. most commonly a female that is on a hardcore PMSing spree. who throws paint on you, throws around racial slurs, and basically treats you like wet, runny diarrhea shit. estrogen bitches make the most masculine men curl up into a ball and cry like little pussies. Most men have allergic reactions to this specimine of bitch, most common symptoms are itchy balls and an ingrown penis.
Jo-yo anna is such an estrogen bitch
Tom-fuck yeah. She's a candy ass, estrogen bitch!
by bear butte August 01, 2006
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