ESA
E.S.A East side assasin used by taggers in china town to represent u from the east side or can be used if you are from the N.Y. representin that your a East sider.
Man those ESA thugs be taggin all ova the West side ova n out.
by My NgUyen AkA Fo ReAlz February 28, 2005

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Top Definition
esa
homegirl, female form of esa
esa loca !
by Anonymous September 28, 2003

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ESA
Esa means a Mexican homegirl.
Using esa is for females if u wanna call a homeboy its ese.
However not all homies use this.
Note that not all use this term.
Another term for esa would be homita which can also mean lil homegirl using it for a male it would be homito.
some other Centro Americans use these terms as well.
But are mainly used by Mexican homies.
Ahi esa that vato over there looks real firme.
by ESA SPOOKY February 27, 2008

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Esa
The Arabic translation of Jesus.
People with this name are badasses and are highly respected.p.s it is usually spelled "Isa"
"Esa. You're the best!
by Rayman3000 September 28, 2013

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esa
female mexican homegirl. feminine of ese.
"Don't worry bout those putas, I got your back, esa."
by South Fizzle Rizzle November 19, 2007

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ESA
Etobicoke School of the Arts
im a great singer so i got into ESA for music theatre
by richygoodman April 30, 2011

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Esa
Esa is your "homegirl". She will be straight with you and will be loyal till the end. Esa is the weird/fun one in the group. She will always have your back. Everyone wants to be Esa's friend. She may be weird but she is amazing. She see the good in everything. She
Is crazy too. But you will love her. She will stand up for you. She has no problem protecting the ones she loves. Don't take her for granted!
Esa is my best-friend.
by Qwerty yippie March 29, 2015

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ESA
Electronic Software Association. Formerly known as the IDSA. An evil watchdog organization hired by insecure gaming corporations to seek out and destroy abandonware sites instead of focusing on real problems like the piracy of current retail software.
"The only good thing ESA ever did was invent the ESRB rating system."
by T.Ractorhead November 24, 2006

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