Top Definition
The option of last resort after following a donkey trail in a desert for many days.
I'd been walking for 17 days. I had water but no food. The hoofprints seemed to be leeding nowhere. Then I saw it - I just had to eat that mule shit.
by robcraine March 15, 2004
1 more definition
A response when you have no other come backs
Ken "Your mom is hot"
Terry "Eat that mule shit!!!"
by Terry Young February 18, 2003

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