Short for "don't understand your abbreviation(s)" or "don't understand your acronym(s)." Pronounced doo-ya - as in, "Do ya think you could stop using so many trite abbreviations, dumbsh*t?"
Cutesie chatter and/or emailer: I wish I could put those annoying animated smiley emoticons in everything I write IYSWIM ROFMAO
Annoyed responder: DUYA?
dick up your ass
Take that duya out, you asshole!
You sound like you have a duya.