Top Definition
Marijuana from Durban, South Africa.
I just smoked some Durban Poison that my friend smuggled from South Africa. Now that is some quality weed.
by ikilled50cent April 18, 2005
1 more definition
Probably the strongest weed you will ever have heard of, smoked, eaten, or whatever, you can't go wrong with that sh!t!

the good strain has a red tinge to the leaves, and the slightly cr@ppier version has a brown tinge. they are both insanely strong, and are grown in South Africa, the best country in the world
dude : Oh man, that Durban poison sure was good...

dude2 : ...

dude : hello?

dude2 : ...
by Ih8ppl April 19, 2005

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