A long, thick, uncircumcised penis; The best sex any member of the female species could hope for.
That guy had quite the duffus!

I had some duffus last night..... it was phenomenal!
by imsothug April 29, 2011
Name for the worst people in existence, also name for vagina or something thats broken.
Duff: "My name is @##$ Duffus"
Bystandard: "How do you sleep at night"
by Patrick!@#$%%^^ April 13, 2006

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