A disruption of sleep patterns caused by the inability to sleep one night due to the prolonged or excessive use of certain drugs, typically stimulants such as speed or coffee.

Similar to jet lag, only much harder to explain to loved ones.
"I did some speed on Saturday night. Now it's 6 am on Tuesday morning, and my drug lagged self is posting some stupid definition on UrbanDictionary.com."
by TwiceBjørn™ January 17, 2005
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Similar to jet lag, when you've spent so long on pharmaceutical remedies you forget where who and what you are while everyone expected you to do exactly what they did and not ended up with individual issues and personal problems
I've got a case of drug lag this has to be a mistrial as somehow I get a virus and now my whole life falls apart
by Cody5050 February 13, 2022
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