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1.
when schools have the police search everybody's lockers for drugs, alcohol, tobacco, etc. the students and teachers are to remain in classrooms until the search is done. you can get in serious trouble if you're caught possessing any of these items.
hannah and britney were caught with weed and booze in their lockers when the school had a random drug bust this week.
by coolkidbb911 February 01, 2009
 
2.
An interjection of negative connotation.
Oh, rent was due today? Drug bust!
by AJ Omaits December 10, 2008