A drive-by shooting (or drive-by for short) is a personal attack carried out by an individual or individuals from a moving or momentarily stopped vehicle. It often results in the shooting of innocent bystanders because the objective is to overwhelm the target by a sudden, massive amount of firepower without attention to accuracy. Usually happens in Detroit.
"Man, did you see that guy and his lady get lit up in Detroit when they were in the wrong neighborhood?"
"Ya, man. That was a serious drive-by shooting."