Anne: Um, you look fine.
Rob: Yeah, shut the fuck up. My sister has Down's syndrome.
Poor muscle tone
Slanting eyes with folds of skin at the inner corners (called epicanthal folds)
Hyperflexibility (excessive ability to extend the joints)
Short, broad hands with a single crease across the palm on one or both hands
Broad feet with short toes
Flat bridge of the nose
Short, low-set ears
Small oral cavity
Short, high-pitched cries in infancy
Sufferers of Downs Syndrome are usually smaller than their normal peers and their physical and intellectual development is ussually slower.
"Her brother is a downsy."