Poor muscle tone
Slanting eyes with folds of skin at the inner corners (called epicanthal folds)
Hyperflexibility (excessive ability to extend the joints)
Short, broad hands with a single crease across the palm on one or both hands
Broad feet with short toes
Flat bridge of the nose
Short, low-set ears
Small oral cavity
Short, high-pitched cries in infancy
Sufferers of Downs Syndrome are usually smaller than their normal peers and their physical and intellectual development is ussually slower.
"Her brother is a downsy."
Anne: Um, you look fine.
Rob: Yeah, shut the fuck up. My sister has Down's syndrome.