A playful, almost gentle way to refer to a person with Down's Syndrome. It can also refer to someone who acts as though they have Down's Syndrome.

Can be used as an adjective or a noun.
Ex: I wish I was a downsie. Then I could be put in a "special" home and be taken care of for the rest of my days. Responsibility is so overrated.

Ex: You are soooo downsie! I can't believe you forgot how to ride a bicycle!
by chrismarcar March 09, 2007
To be a downer
To always be getting people down
Why you gotta be so downsie all the time......... BITCH
by QUIEZ January 09, 2009

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