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1.
Even god finds them funny.
Down's syndrome kid: "Help me, my eyes are r8 small but ma head's pure massive"
Guy watching: "Hahaha oh my god you should be put down."
by sdw298 May 05, 2008
 
2.
a severe case of retardation often the result of years of marijuana abuse to the brain.
i didnt know uc davis' marijuana economy was doing so well. that explains why so many of their students have down's syndrome.
by mikechen August 18, 2006